What is Anastrozole?
Anastrozole, is a research liquid currently being tested on animal test subjects for its property in affecting estrogen receptors. Not being naturally found, it is synthesized in the laboratory and has a potential in interrupting the ability of breast cancer tumors to grow in female animal test subjects. Anastrozole works by reducing the amount of estrogen, as it is an aromatase inhibitor. It’s ability to decrease the production of estrogen has lead to studies on its effects of hyperplasia and metastasis.
Breast cancer is a cancer that forms in the tissues of the breast, most commonly this will be found in the ducts and the lobules. This disease causes an uncontrollable growth of cells in tissue, forming a tumor. It is one of the leading causes of death in the world.
It has been found that breast cancer is greatly affected by the presence of estrogen. Both being stimulated and maintained by this presence. Anastrozole, as well as most other breast cancer research liquids, have shown to work by inhibiting the synthesis of estrogen in animal test subjects.
Anastrozole Mechanism of Action
Most breast cancers are caused and maintained by the presence of estrogen, which is why the female animal test subjects are more commonly the victims of this type of cancer more than male animal test subjects. It is found in those who have gone through menopause; estrogens are created using an enzyme called aromatase. This enzyme converts adrenal androgens to estrone and estradiol. Inhibiting the aromatase enzyme in the tissue around and in the tumor will, therefore, suppress the estrogen biosynthesis in the area causing a reduction of the tumor.
As a select no-steroidal aromatase inhibitor, Anastrozole works by significantly lowering the concentration of estradiol in the blood, which may cause a reduction of size and a decrease of growth in the tumor. Specifically, Anastrozole will bind to the aromatase enzyme through competitive inhibition, to block the process of androgens being converted to estrogen.
Common Uses for Anastrozole
After being tested on animal research subjects, research liquids are usually developed to help increase the livelihood of those who diseases and disorder. A serious disease that has been one of the leading causes of death is cancer. There are a number of different cancers that need to be researched worldwide.
Through studies, this research liquid has been found to be a potential preventive measure for breast cancer in animal test subjects who are at high risk of developing it, due to genetics and other factors. However, it has also been discovered to be helpful in male animal test subjects to treat excessive estrogen, which can lead to serious health problems, and to treat younger animal test subjects who suffer from hormonal problems.
Continued Research for Anastrozole
It has been found that excess estradiol in male animal test subjects can lead to serious problems including increased risk of stroke, heart attack, prostate cancer, and other symptoms. Due to this, Anastrozole has been tested on animal test subjects for reducing estradiol.
Studies are currently still needed to find potential uses for this research liquid.
Anastrozole Side Effects
Most research liquids that are used for researching treatments for disorders will have some sort of side effects. With Anastrozole, some of these side effects are more common than other:
- Dry mouth
- Bone pain
Other side effects are more serious and can lead to major health issues. Here is a list of some of the more serious side effects that Anastrolzole can cause:
- Blurred vision
- Chest pain
- Decrease or increase in heartrate
- Shortness of breath
- Feet and leg swelling
- Pain in arms, back, or jaw
- Trouble urinating
- Increased blood pressure
- Weight gain
- Bone weakness
- Vaginal bleeding
A common side effect of this research liquid is bone weakness. It is reported to be the cause of more fractures than another common breast cancer research liquid such as Tamoxifen. To combat this, sometimes other drugs, such as bisphosphonates, are administered to animal test subjects.
As with all most research liquids, Anastrozole can have serious negative effects. Researchers should be vigilant with the dosage to animal test subjects. Not every subject will react the same way to the peptide, and some can be expected to experience more symptoms than others.
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